Magnetic 3D Cell Culture: Tools to Bridge the Gap Between 2D and 3D

The growing push for 3D cell culture models is limited by technical challenges in handling, processing, and scalability to high-throughput applications. To meet these challenges, Greiner Bio-One offers an innovative technology called  magnetic 3D bioprinting, in which cells are individually magnetized and assembled with magnetic forces without changing the phenotype or the physiology of these cells. Magnetization of cells not only makes routine cell culture and experiments feasible and scalable, but also enables scientist to have fine spatial control in the formation of spheroids or more complex structures.

This presentation will focus on recent developments using magnetic 3D bioprinting, particularly in cancer biology and immunology. Specifically, it will demonstrate a method for phenotypic profiling of cell types within spheroids using real-time high-throughput imaging.

Learning Objectives:

/ General technique of magnetic 3D cell culture and magnetic 3D bioprinting

/ Key advantages of 3D cell culture over other techniques

/ Broad applications of 3D cell culture

/ Applications in immunobiology

/ Comparison between magnetic 3D cell culture and in vivo results in collaboration with MD Anderson Cancer Center

Speaker: 

Glauco R. Souza, PhD
Director of Global Business Developement and Innovation - Greiner Bio-One